1 Global Oxidized Regenerated Cellulose Market Size (Value) and CAGR (2024-2033)
In 2024, the global Oxidized Regenerated Cellulose market was valued at USD 394.48 million, with a CAGR of 8.32% from 2024 to 2033.
Oxidized Regenerated Cellulose (ORC) is a water-insoluble derivative of cellulose with excellent biocompatibility, biodegradability and non-toxicity. It can be produced from cellulose by the action of an oxidizing agent. Oxidized Regenerated Cellulose is mainly used as a surgical hemostatic material.
Figure Global Oxidized Regenerated Cellulose Market Size (M USD) and CAGR 2024-2033

2 Oxidized Regenerated Cellulose Market Drivers
One of the primary drivers is the increasing number of surgical procedures worldwide. ORC is an effective hemostatic material that does not rely on the normal coagulation mechanism in the human body. Instead, it rapidly promotes blood coagulation through physical action, effectively controlling small blood vessel bleeding. This unique characteristic makes it highly valuable in surgical settings, especially as the number of surgeries continues to rise due to factors such as an aging global population and increasing incidences of chronic diseases like cancer.
Another significant driver is the growing demand for effective and reliable hemostatic agents in the medical industry. ORC is known for its rapid hemostasis, complete absorption within the body, and ease of use. These properties make it a preferred choice for surgeons and medical professionals. The soft texture of ORC allows it to be trimmed into any shape that fits the bleeding site, improving the hemostasis effect and helping to form a thrombus to achieve rapid hemostasis. This versatility and effectiveness contribute to its widespread adoption in various surgical procedures, including those in the fields of oncology, gynecology, and cosmetic surgery.
3 Oxidized Regenerated Cellulose Market Restraints
Despite its numerous advantages and growing demand, the Oxidized Regenerated Cellulose (ORC) market faces several limitations that can hinder its growth and expansion. One of the primary limitations is the high technical content required for its production. ORC is obtained through a selective oxidation process using regenerated cellulose material as raw material. This process involves complex technology, equipment, and environmental protection measures.
The fast reaction speed and the need to maintain the integrity and strength of the fibers during oxidation pose significant challenges. Additionally, ensuring uniform oxidation of regenerated cellulose is difficult, and the resulting material often has high entanglement rates and brittleness, making it challenging to form into usable products. These technical difficulties create barriers to entry for new players in the market.
ORC products are primarily used in the medical field, which is heavily regulated. Products must undergo multiple procedures for monitoring and certification from research and development to commercialization. These regulatory requirements ensure the safety and efficacy of ORC products but also limit the speed at which new products can enter the market and increase costs for manufacturers.
Cost is another significant limitation. Rising energy prices, driven by global events such as the conflict between Russia and Ukraine, have led to increased production costs for ORC manufacturers. The production and operation of ORC involve the use of energy resources like water and electricity, and fluctuations in energy prices directly impact production costs. This makes cost control and inventory management more challenging for manufacturers, potentially affecting the market’s overall growth.
4 Global Oxidized Regenerated Cellulose Market Size by Type in 2024
In 2024, the global ORC market is projected to reach a total value of 394.48 million USD. The segmentation by type reveals a clear dominance of cotton-derived ORC. Specifically, the Originated From Cotton segment is anticipated to hold a market value of 340.37 million USD, accounting for approximately 86.3% of the total market. This substantial market share underscores the prevalence and preference for cotton-based ORC products in various applications, particularly within the medical industry.
Cotton-derived ORC is produced using high-grade cotton fibers as the raw material. These fibers undergo a selective oxidation process, which imparts hemostatic properties to the material. This type of ORC is highly valued for its purity, effectiveness in promoting rapid blood coagulation, and biocompatibility. It is widely used as a hemostatic agent during surgical procedures due to its ability to be easily trimmed and shaped to fit the bleeding site, ensuring optimal contact and effective hemostasis.
The Others category, which includes ORC products derived from sources other than cotton, is projected to have a market value of 54.10 million USD in 2024, representing approximately 13.7% of the total market. This category encompasses ORC derived from alternative plant-based materials or synthetic sources. While these types of ORC may offer similar hemostatic properties, they often differ in terms of raw material availability, production processes, and specific applications. The market share of this category is relatively smaller compared to cotton-derived ORC, primarily due to the established preference and widespread use of cotton-based products in the medical industry.
Table Global Oxidized Regenerated Cellulose Market Size by Type in 2024
Type | Market Size (M USD) 2024 |
Originated From Cotton | 340.37 |
Others | 54.10 |
5 Global Oxidized Regenerated Cellulose Market Size by Application in 2024
The primary application of Oxidized Regenerated Cellulose is in the medical industry, where it is used extensively as a hemostatic agent. In 2024, the medical industry segment is expected to have a market value of 384.86 million USD, accounting for approximately 97.6% of the total ORC market. This significant share is driven by the increasing number of surgical procedures worldwide, the growing demand for effective hemostatic materials, and the aging global population, which leads to a higher incidence of chronic diseases requiring surgical interventions.
ORC’s effectiveness in controlling bleeding during surgeries, its biocompatibility, and its ability to be absorbed by the body make it an ideal choice for medical applications. It is used in various surgical procedures, including general surgery, neurosurgery, urology, gynecology, and reconstructive surgery. The material’s ability to be easily trimmed and shaped to fit the bleeding site further enhances its appeal in these applications.
Table Global Oxidized Regenerated Cellulose Market Size by Application in 2024
Application | 2024 |
Medical industry | 384.86 |
Others | 9.62 |
6 Global Oxidized Regenerated Cellulose Market Size by Region in 2024
North America continues to dominate the global ORC market, with a projected market value of 152.03 million USD in 2024. This region’s leadership is driven by its advanced healthcare infrastructure, high demand for medical products, and strong purchasing power. The United States, in particular, is a major consumer of ORC due to its large number of surgical procedures and the presence of leading medical device manufacturers. The market in North America is characterized by high competition and a focus on innovation and product development.
Europe is the second-largest market for ORC, with a projected value of 99.2 million USD in 2024. Europe’s well-developed healthcare systems and stringent regulatory environment drive the demand for high-quality ORC products. Countries like Germany, the United Kingdom, and France are significant consumers of ORC. The European market is characterized by a strong emphasis on product quality and regulatory compliance, which drives the demand for high-quality ORC materials. Technological advancements and a focus on innovation also contribute to the region’s market growth.
China is experiencing rapid growth in its ORC market, with a projected value of 60.09 million USD in 2024. China’s expanding healthcare sector and increasing investment in medical research and development are key drivers of this growth. The country’s large population and growing middle class contribute to the increasing demand for medical products, including ORC. China’s market is characterized by a mix of domestic and international players, with a focus on cost-effective solutions and technological advancements.
Figure Global Oxidized Regenerated Cellulose Market Size by Region in 2024

7 Major Players in Global Oxidized Regenerated Cellulose Market
7.1 Ethicon
Ethicon is a subsidiary of Johnson & Johnson, a global leader in medical devices. Established in 1949, Ethicon is headquartered in the United States and operates worldwide. The company is renowned for its surgical sutures and wound closure devices, and its ORC product, SURGICEL® FIBRILLAR Absorbable Hemostat, is highly regarded in the medical community. This product is designed to provide rapid hemostasis and is effective in controlling bleeding during surgical procedures. In the most recent year, Ethicon reported a production value of 269.40 million USD and a gross margin of 69.77%.
7.2 GELITA MEDICAL
GELITA MEDICAL, founded in 1875, is a German company specializing in the development and production of absorbable hemostats based on gelatin and oxidized cellulose. Headquartered in Eberbach, Germany, GELITA MEDICAL operates globally and is known for its high-quality products. The company’s ORC product, GELITA-CEL®, is a natural and safe hemostat made from 100% biodegradable organic oxidized cellulose. This product is effective in inducing hemostasis and reducing the risk of infection due to its low pH. In the most recent year, GELITA MEDICAL reported a production value of 17.28 million USD and a gross margin of 65.29%.
7.3 Samyang Holdings Biopharmaceuticals Division
Samyang Holdings Biopharmaceuticals Division is a South Korean company engaged in the development and commercialization of advanced medical technologies and pharmaceuticals. Established in 1992, Samyang is headquartered in Seongnam-si, South Korea, and operates primarily in the Asia-Pacific region. The company’s ORC product, SurgiGuard®, is an ISO 13485 and CE Mark approved hemostat designed to assist in controlling capillary, venous, and small arterial hemorrhage. In the most recent year, Samyang reported a production value of 9.22 million USD and a gross margin of 60.59%.