1 Global Hyaluronic Acid Raw Material Market Size (Value) and CAGR (2024-2033)
In 2024, the global Hyaluronic Acid Raw Material market was valued at USD 714.43 million, with a CAGR of 17.3% from 2024 to 2033.
There are two main sources of Hyaluronic acid the first being animal extracted (from Rooster Combs typically) and the second being bacterial fermentation. The hyaluronic acid molecule of hyaluronic acid can carry more than 500 times of water, so it is a high-quality moisturizing ingredient with extremely high clinical application value. Hyaluronic acid, as a functional raw material, is widely used in various fields.
Hyaluronic acid with a larger molecular weight has stronger moisturizing properties, anti-falling properties and viscoelasticity, so it is often used as a filling material in medical beauty. Hyaluronic acid with a small molecular weight can be directly absorbed by the skin, so it is often used in moisturizing skin care products.
Figure Global Hyaluronic Acid Raw Material Market Size (M USD) and CAGR 2024-2033
2 Hyaluronic Acid Raw Material Market Drivers
Hyaluronic acid has become a cornerstone in the field of medical aesthetics due to its unique properties. Cross-linked hyaluronic acid, in particular, is favored for its biocompatibility, long degradation time, and effective filling capabilities. It has gradually replaced traditional fillers like collagen and is now widely used in non-surgical cosmetic procedures such as wrinkle removal, lip augmentation, and facial contouring. The growing awareness of medical aesthetics, coupled with increasing disposable incomes and a higher acceptance of non-invasive treatments, has significantly boosted the demand for hyaluronic acid raw materials.
The global population is aging rapidly, with many countries experiencing a significant increase in the proportion of elderly individuals. This demographic shift has led to a higher prevalence of age-related diseases such as osteoarthritis, which affects millions of people worldwide. Hyaluronic acid is FDA-approved for treating knee osteoarthritis through intra-articular injections, making it a critical component in managing joint health. The increasing demand for therapeutic solutions to address these health issues has further fueled the market for hyaluronic acid raw materials.
Hyaluronic acid’s unparalleled ability to retain moisture makes it an ideal ingredient in the cosmetics industry. It can absorb up to 1,000 times its weight in water, providing superior hydration and skin protection. This unique property has led to its widespread use in skincare products such as serums, creams, and masks. Additionally, hyaluronic acid helps reduce UV transmission and repair skin damage, making it a popular choice for consumers seeking effective skincare solutions. The continuous innovation and development of new cosmetic products containing hyaluronic acid have further driven the market’s growth.
3 Hyaluronic Acid Raw Material Market Challenges
The production of hyaluronic acid raw material is a complex process that requires advanced technological capabilities and strict quality control measures. The industry is characterized by high technical barriers, making it difficult for new entrants to master the production techniques and achieve large-scale manufacturing. The need for precision in fermentation, purification, and molecular weight control poses significant challenges for new companies, limiting market competition to a few established players.
The Hyaluronic Acid Raw Material market is highly competitive, with several major players dominating the industry. These companies invest heavily in research and development, product innovation, and marketing strategies to maintain their market share. The intense competition has led to aggressive pricing strategies and a constant need for innovation to stay ahead. Smaller companies often struggle to compete with larger firms, which have greater resources and brand recognition.
Hyaluronic acid is used in medical and cosmetic products, which are subject to stringent regulatory requirements. Ensuring product safety, quality, and compliance with international standards is a critical challenge for manufacturers. Regulatory scrutiny can lead to delays in product approvals and increased costs. Additionally, concerns about the safety and efficacy of hyaluronic acid products can impact consumer confidence and market adoption.
4 Global Hyaluronic Acid Raw Material Market Size and Share by Type in 2024
Microbial fermentation is the dominant method for producing hyaluronic acid raw materials, accounting for nearly the entire market share. In 2024, the market size for hyaluronic acid produced through microbial fermentation is projected to be 710.93 million USD, representing approximately 99.51% of the total market. This method involves using microorganisms, typically strains of Streptococcus, to ferment glucose and produce hyaluronic acid.
The resulting product is highly pure and can be tailored to various molecular weights, making it suitable for a wide range of applications, including cosmetics, medical treatments, and dietary supplements. The ability to control the molecular weight through fermentation conditions and subsequent processing allows manufacturers to produce hyaluronic acid with specific properties, such as high viscosity for medical applications or low molecular weight for skincare products.
On the other hand, hyaluronic acid derived from animal tissues holds a much smaller market share. In 2024, the market size for animal-derived hyaluronic acid is estimated at 3.50 million USD, representing only 0.49% of the total market. This type of hyaluronic acid is extracted from natural sources such as rooster combs, umbilical cords, and synovial fluid. While animal-derived hyaluronic acid was historically the primary source, its use has diminished due to several limitations. The extraction process is complex and yields lower quantities compared to microbial fermentation. Additionally, animal-derived hyaluronic acid is more susceptible to contamination and variability in quality. These factors, combined with ethical and regulatory concerns, have led to a preference for microbial fermentation in the industry.
Table Global Hyaluronic Acid Raw Material Market Size and Share by Type in 2024
Type | Market Size (M USD) 2024 | Market Share 2024 |
Microbial Fermentation | 710.93 | 99.51% |
Animal Tissue | 3.50 | 0.49% |
5 Global Hyaluronic Acid Raw Material Market Consumption and Share by Application in 2024
In the cosmetics sector, hyaluronic acid is renowned for its moisturizing and anti-aging properties. It is widely used in skincare products such as serums, creams, and masks, as well as in makeup items like lipsticks and foundations. The ability of hyaluronic acid to retain moisture and enhance skin elasticity makes it a crucial ingredient in the beauty industry. In 2024, the consumption of hyaluronic acid raw material in the cosmetics sector is expected to reach 580.3 MT, accounting for approximately 46.28% of the total market. This segment is driven by the increasing demand for effective skincare solutions and the growing awareness of the benefits of hyaluronic acid in maintaining youthful skin.
Dietary supplements represent the largest application segment for hyaluronic acid raw material. These supplements are used to support joint health, improve skin hydration, and enhance overall well-being. The growing health consciousness among consumers and the increasing demand for natural supplements have driven the adoption of hyaluronic acid in this sector. In 2024, the consumption of hyaluronic acid raw material in dietary supplements is expected to reach 628.6 MT, accounting for 50.13% of the total market. This segment is expected to continue growing as consumers become more aware of the health benefits of hyaluronic acid.
Table Global Hyaluronic Acid Raw Material Market Consumption and Share by Application in 2024
Application | Market Consumption (MT) 2024 | Market Share 2024 |
Cosmetics | 580.3 | 46.28% |
Medical | 45.0 | 3.59% |
Dietary Supplement | 628.6 | 50.13% |
6 Global Hyaluronic Acid Raw Material Market Demand by Region in 2024
North America is a prominent market for hyaluronic acid raw materials, with a demand of 250.6 MT in 2024. This region’s market is primarily driven by the United States and Canada, where the cosmetics and medical industries have a strong presence. The demand is fueled by the high disposable incomes of consumers, who are increasingly investing in skincare products and medical treatments that utilize hyaluronic acid. Additionally, the region’s robust healthcare infrastructure and focus on innovation in the medical and cosmetic sectors further support the market’s growth. North America is known for its early adoption of new technologies and products, making it a key driver of the global market.
Europe is another significant region, with a projected demand of 278.2 MT in 2024. European countries, particularly Germany, France, and the UK, have a high demand for hyaluronic acid raw materials, driven by the region’s strong cosmetics and pharmaceutical industries. The European market is characterized by stringent regulatory standards, which ensure high product quality and safety. This regulatory environment has led to a preference for high-purity and high-quality hyaluronic acid products. The aging population in Europe also contributes to the demand for medical applications of hyaluronic acid, such as joint treatments and aesthetic procedures.
Asia-Pacific is the largest regional market for hyaluronic acid raw materials, with a projected demand of 575.3 MT in 2024. This region’s market is dominated by China and Japan, which are major producers and consumers of hyaluronic acid. China, in particular, has experienced rapid economic growth, leading to increased disposable incomes and a growing middle class. This has resulted in a surge in demand for cosmetics, dietary supplements, and medical treatments that contain hyaluronic acid.
Figure Global Hyaluronic Acid Raw Material Market Demand by Region in 2024
7 Major Players in Global Hyaluronic Acid Raw Material Market
7.1 Bloomage Biotech
Company Profile: Bloomage Biotech is a leading global manufacturer of hyaluronic acid, integrating R&D, production, and sales. Established in 2000 and based in China, the company has positioned itself as a dominant player in the industry, leveraging advanced bio-fermentation technology to produce high-quality hyaluronic acid products. Bloomage Biotech offers a wide range of products, including low and high molecular weight hyaluronic acid, catering to diverse applications in cosmetics, pharmaceuticals, and dietary supplements.
Business Overview: Bloomage Biotech’s business is built on a robust bio-fermentation platform, enabling the production of over 200 specifications of hyaluronic acid. The company’s products are widely used in medical devices, cosmetics, and functional foods, reflecting its commitment to innovation and quality. Bloomage Biotech’s global market reach is supported by its extensive R&D capabilities and strategic partnerships.
Product Introduction: Bloomage Biotech’s flagship products include Hybloom™ Hydrolyzed Hyaluronic Acid (HA-TLM 3-5), known for its excellent moisturizing properties and transdermal absorption capabilities. The company also offers Hybloom™ Low Molecular Weight Sodium Hyaluronate and Hybloom™ High Molecular Weight Sodium Hyaluronate, tailored for specific applications in skincare and medical treatments.
In the last two years, Bloomage Biotech has demonstrated strong financial performance. In 2020, the company reported a revenue of 107.55 million USD with a gross margin of 78.09%. By 2021, its revenue grew to 129.99 million USD, and the gross margin slightly increased to 78.60%.
7.2 HTL Biotechnology
Company Profile: HTL Biotechnology, established in 1992 and based in France, is a world leader in the production of pharmaceutical-grade hyaluronic acid. The company specializes in producing high-purity hyaluronic acid through fermentation, offering products with a wide range of molecular weights to meet diverse clinical and research needs.
Business Overview: HTL Biotechnology’s business is centered on providing high-quality, tailor-made hyaluronic acid products for the pharmaceutical and medical device industries. The company’s commitment to excellence is reflected in its stringent quality control measures and compliance with international standards. HTL Biotechnology’s global market presence is supported by its advanced production facilities and strong R&D capabilities.
Product Introduction: HTL Biotechnology’s products are known for their high purity and consistency, with molecular weights ranging from 8 kDa to 4.5 MDa. The company offers both low and high molecular weight hyaluronic acid, suitable for applications in ophthalmology, orthopedics, and aesthetic medicine. HTL Biotechnology’s products are designed to meet the highest standards of safety and efficacy.
In the last two years, HTL Biotechnology has maintained a strong financial position. In 2020, the company reported a revenue of 47.92 million USD with a gross margin of 70.41%. By 2021, its revenue increased to 58.95 million USD, and the gross margin remained robust at 70.64%.
7.3 Contipro
Company Profile: Contipro, established in 1990 and based in Europe, is a well-known producer of hyaluronic acid for the pharmaceutical and cosmetic industries. The company has built a strong reputation for its high-quality products and extensive R&D capabilities. Contipro’s global market presence is supported by its large research and development center and a network of over 100 researchers.
Business Overview: Contipro’s business focuses on the production of hyaluronic acid through microbial fermentation, ensuring high purity and consistency. The company’s products are widely used in tissue engineering, wound healing, and drug delivery, reflecting its commitment to innovation and quality. Contipro’s global market reach is supported by its extensive marketing network and strong partnerships with leading companies.
Product Introduction: Contipro’s flagship product is Sodium Hyaluronate, produced through the fermentation of non-GMO Streptococcus Zooepidemicus. The company offers a range of hyaluronic acid products with different molecular weights, suitable for applications in cosmetics, pharmaceuticals, and medical devices. Contipro’s products are known for their high quality and compliance with international standards.
In the last two years, Contipro has demonstrated consistent financial performance. In 2020, the company reported a revenue of 38.12 million USD with a gross margin of 85.37%. By 2021, its revenue increased to 46.37 million USD, and the gross margin remained high at 81.97%.